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Patients who are pregnant or breastfeeding, have a history of medullary thyroid cancer or MEN-2 syndrome, severe gastroparesis, or certain pancreatic conditions may not be candidates

People with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 are not candidates, which is one reason supervised prescribing matters

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Finally, these medications stimulate insulin production and regulate blood sugar levels, so your cells use glucose for energy rather than storing it as fat