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With 476,857 individuals across 18 different countries (propensity score matched 1:1 with pregnant controls), this is the largest study to date in this historically underserved population

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Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction